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Nestin-expressing bm-MSCs have been shown to express high levels of SDF-1, stem cell factor (SCF), angiopoietin-1 (ang-1), interleukin-7, vascular cell adhesion molecule 1 (VCAM-1), and osteopontin (OPN), which are applied for [url=https://StemCellTherapyInCanada.com/]https://StemCellTherapyInCanada.com/[/url]. directly participates in the regulation and maintenance of HSC rest.336 Depletion of the amount of MSCs in the bone marrow leads to the mobilization of HSCs into the peripheral bloodstream and the spleen.
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